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Serine protease inhibitor Kazal-type 6 levels (SPINK6.5731.1.3)

FBXO38-DT · rs1432688

What the study found

Who was studied 3,301 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 1.06 higher (95% confidence interval 0.98-1.14); p = 8 × 10−135.

How common The G allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 5, band 5q32 — in an intron of FBXO38-DT.

What each result means

A/A No copy of the version the research linked to Serine protease inhibitor Kazal-type 6 levels (SPINK6.5731.1.3). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Serine protease inhibitor Kazal-type 6 levels (SPINK6.5731.1.3). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Serine protease inhibitor Kazal-type 6 levels (SPINK6.5731.1.3). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1432688

What is rs1432688?

rs1432688 is a single position in the genome, in or near the FBXO38-DT gene. Published research associates it with serine protease inhibitor kazal-type 6 levels (spink6.5731.1.3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1432688 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1432688 come from?

GWAS Catalog, Nature 2018, PMID:29875488. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Serine protease inhibitor Kazal-type 6 levels (SPINK6.5731.1.3) (rs1432688). MyGeneLog™. https://www.mygenelog.com/variants/rs1432688

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