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TNN protein levels

SLC9C2 · rs143195788

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.464 higher (95% confidence interval 0.35-0.58); p = 3 × 10−20.

How common The G allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 1, band 1q25.1 — in an intron of SLC9C2.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of TNN protein levels — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with TNN protein levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of TNN protein levels compared to the general population.
Source

Questions about rs143195788

What is rs143195788?

rs143195788 is a single position in the genome, in or near the SLC9C2 gene. Published research associates it with tnn protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs143195788 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs143195788 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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TNN protein levels (rs143195788). MyGeneLog™. https://www.mygenelog.com/variants/rs143195788

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