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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 7,681 Finnish ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.139 SD units higher; p = 2 × 10−14.
Where it sits Chromosome 4, band 4q21.1 — in an intron of SHROOM3.
What each result means
A/ANo copy of the version the research linked to Interleukin-10 levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Interleukin-10 levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Interleukin-10 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of human genetics · 2017 · PMID 27989323
Questions about rs143141511
What is rs143141511?
rs143141511 is a single position in the genome, in or near the SHROOM3 gene. Published research associates it with interleukin-10 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs143141511 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs143141511 come from?
GWAS Catalog, American journal of human genetics 2017, PMID:27989323. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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