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Who was studied 80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 3.64 higher; p = 4 × 10−8.
Where it sits Chromosome 12, band 12q13.2 — in an intron of SARNP.
What each result means
A/ATwo copies of the version the research linked to Pulse pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Pulse pressure. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Pulse pressure. This is the starting point the study compared everyone against.
Nature genetics · 2017 · PMID 27841878 · open access
Questions about rs143118162
What is rs143118162?
rs143118162 is a single position in the genome, in or near the SARNP gene. Published research associates it with pulse pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs143118162 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs143118162 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs143118162 come from?
GWAS Catalog, Nat Genet 2016, PMID:27841878. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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