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Who was studied 8,393 European ancestry individuals; replicated in 1,023 African American individuals, 491 Hispanic individuals.
The effect
Each copy of the T allele shifted the measure 1.68 lower (95% confidence interval 1.36-2); p = 4 × 10−25.
How common The T allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 6, band 6p22.3 — between genes, 6.4 kb from NHLRC1.
What each result means
C/CNo copy of the version the research linked to Intrinsic epigenetic age acceleration. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Intrinsic epigenetic age acceleration. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Intrinsic epigenetic age acceleration. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2018 · PMID 29374233 · open access
Questions about rs143093668
What is rs143093668?
rs143093668 is a single position in the genome, in or near the KIF13A gene. Published research associates it with intrinsic epigenetic age acceleration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs143093668 linked to?
On MyGeneLog this position is linked to Telomere Length and Epigenetic Age Acceleration. The research behind each link, and its sources, are set out on that condition page.
Does having rs143093668 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs143093668 come from?
GWAS Catalog, Nat Commun 2018, PMID:29374233. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 35117223217Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others17Total35Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Intrinsic epigenetic age acceleration (rs143093668). MyGeneLog™. https://www.mygenelog.com/variants/rs143093668