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Pulse pressure

MYEOV · rs143082869

What the study found

Who was studied 225,112 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals; replicated in 445,360 individuals.

The effect Each copy of the G allele shifted the measure 27.6 mmHg higher (95% confidence interval 22.99-32.25); p = 1 × 10−31.

How common The G allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 11, band 11q13.3 — between genes, 55.4 kb from MYEOV.

What each result means

A/A No copy of the version the research linked to Pulse pressure. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Pulse pressure. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Pulse pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs143082869

What is rs143082869?

rs143082869 is a single position in the genome, in or near the MYEOV gene. Published research associates it with pulse pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs143082869 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs143082869 come from?

GWAS Catalog, Nature genetics 2019, PMID:30578418. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Pulse pressure (rs143082869). MyGeneLog™. https://www.mygenelog.com/variants/rs143082869

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