Standard
Lung function (forced vital capacity)
EFEMP1 · rs1430193
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Lung function (forced vital capacity) — no copies of the reported risk allele.
A/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Lung function (forced vital capacity).
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Lung function (forced vital capacity) compared to the general population.
Source
Genome-wide association analysis identifies six new loci associated with forced vital capacity
Loth DW,
Soler Artigas M,
Gharib SA,
Wain LV,
Franceschini N,
Koch B,
Pottinger TD,
Smith AV,
Duan Q,
Oldmeadow C,
Lee MK,
Strachan DP
and 148 more — show all
James AL,
Huffman JE,
Vitart V,
Ramasamy A,
Wareham NJ,
Kaprio J,
Wang XQ,
Trochet H,
Kähönen M,
Flexeder C,
Albrecht E,
Lopez LM,
de Jong K,
Thyagarajan B,
Alves AC,
Enroth S,
Omenaas E,
Joshi PK,
Fall T,
Viñuela A,
Launer LJ,
Loehr LR,
Fornage M,
Li G,
Wilk JB,
Tang W,
Manichaikul A,
Lahousse L,
Harris TB,
North KE,
Rudnicka AR,
Hui J,
Gu X,
Lumley T,
Wright AF,
Hastie ND,
Campbell S,
Kumar R,
Pin I,
Scott RA,
Pietiläinen KH,
Surakka I,
Liu Y,
Holliday EG,
Schulz H,
Heinrich J,
Davies G,
Vonk JM,
Wojczynski M,
Pouta A,
Johansson A,
Wild SH,
Ingelsson E,
Rivadeneira F,
Völzke H,
Hysi PG,
Eiriksdottir G,
Morrison AC,
Rotter JI,
Gao W,
Postma DS,
White WB,
Rich SS,
Hofman A,
Aspelund T,
Couper D,
Smith LJ,
Psaty BM,
Lohman K,
Burchard EG,
Uitterlinden AG,
Garcia M,
Joubert BR,
McArdle WL,
Musk AB,
Hansel N,
Heckbert SR,
Zgaga L,
van Meurs JB,
Navarro P,
Rudan I,
Oh YM,
Redline S,
Jarvis DL,
Zhao JH,
Rantanen T,
O'Connor GT,
Ripatti S,
Scott RJ,
Karrasch S,
Grallert H,
Gaddis NC,
Starr JM,
Wijmenga C,
Minster RL,
Lederer DJ,
Pekkanen J,
Gyllensten U,
Campbell H,
Morris AP,
Gläser S,
Hammond CJ,
Burkart KM,
Beilby J,
Kritchevsky SB,
Gudnason V,
Hancock DB,
Williams OD,
Polasek O,
Zemunik T,
Kolcic I,
Petrini MF,
Wjst M,
Kim WJ,
Porteous DJ,
Scotland G,
Smith BH,
Viljanen A,
Heliövaara M,
Attia JR,
Sayers I,
Hampel R,
Gieger C,
Deary IJ,
Boezen HM,
Newman A,
Jarvelin MR,
Wilson JF,
Lind L,
Stricker BH,
Teumer A,
Spector TD,
Melén E,
Peters MJ,
Lange LA,
Barr RG,
Bracke KR,
Verhamme FM,
Sung J,
Hiemstra PS,
Cassano PA,
Sood A,
Hayward C,
Dupuis J,
Hall IP,
Brusselle GG,
Tobin MD,
London SJ
Nature genetics · 2014 · PMID 24929828
Questions about rs1430193
What is rs1430193?
rs1430193 is a single position in the genome, in or near the EFEMP1 gene. Published research associates it with lung function (forced vital capacity). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1430193 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1430193 come from?
GWAS Catalog, Nat Genet 2014, PMID:24929828. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants