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WFIKKN2 protein levels

near MIR8059 · rs142912248

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.178 lower (95% confidence interval 0.14-0.22); p = 3 × 10−20.

How common The G allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 17, band 17q21.33 — between genes, 8.6 kb from MIR8059.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of WFIKKN2 protein levels — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with WFIKKN2 protein levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of WFIKKN2 protein levels compared to the general population.
Source

Questions about rs142912248

What is rs142912248?

rs142912248 is a single position in the genome, in or near the near MIR8059 gene. Published research associates it with wfikkn2 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs142912248 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs142912248 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

WFIKKN2 protein levels (rs142912248). MyGeneLog™. https://www.mygenelog.com/variants/rs142912248

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