Standard

TIMD4 protein levels

SGCD · rs142855773

Where this position leads

Condition: Celiac Disease

rs142855773 Condition: Celiac Disease Celiac Disease Condition rs142855773 rs142855773 SGCD

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.19 higher (95% confidence interval 0.13-0.25); p = 1 × 10−12.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 5, band 5q33.3 — in an intron of SGCD.

What each result means

A/A Two copies of the version the research linked to TIMD4 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to TIMD4 protein levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to TIMD4 protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs142855773

What is rs142855773?

rs142855773 is a single position in the genome, in or near the SGCD gene. Published research associates it with timd4 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs142855773 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs142855773 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs142855773 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

TIMD4 protein levels (rs142855773). MyGeneLog™. https://www.mygenelog.com/variants/rs142855773

← See all variants