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Progesterone levels

HSD17B12 · rs142754737

What the study found

Who was studied 1,358 European ancestry men, 1,261 European ancestry women.

The effect Each copy of the T allele shifted the measure 0.798 higher (95% confidence interval 0.53-1.07); p = 9 × 10−9.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 11, band 11p11.2 — in an intron of HSD17B12.

What each result means

C/C No copy of the version the research linked to Progesterone levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Progesterone levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Progesterone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs142754737

What is rs142754737?

rs142754737 is a single position in the genome, in or near the HSD17B12 gene. Published research associates it with progesterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs142754737 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs142754737 come from?

GWAS Catalog, The Journal of clinical endocrinology and metabolism 2019, PMID:31169883. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Progesterone levels (rs142754737). MyGeneLog™. https://www.mygenelog.com/variants/rs142754737

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