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Body mass index and triglycerides (pairwise)

STK36 · rs1427445

Where this position leads

Condition: Obesity and Body Weight

rs1427445 Condition: Obesity and Body Weight Obesity and Body Weight Condition rs1427445 rs1427445 STK36

What the study found

Who was studied 500,123 European ancestry individuals,16,962 East Asian, South Asian, Hispanic and African American ancestry individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 3 × 10−13.

How common The A allele had a frequency of about 43% in the people studied.

Where it sits Chromosome 2, band 2q35 — in an intron of STK36.

What each result means

A/A Two copies of the version the research linked to Body mass index and triglycerides (pairwise). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Body mass index and triglycerides (pairwise). That is a smaller link than two copies.
C/C No copy of the version the research linked to Body mass index and triglycerides (pairwise). This is the starting point the study compared everyone against.
Source

Questions about rs1427445

What is rs1427445?

rs1427445 is a single position in the genome, in or near the STK36 gene. Published research associates it with body mass index and triglycerides (pairwise). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1427445 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs1427445 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1427445 come from?

GWAS Catalog, Nat Metab 2021, PMID:33619380. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body mass index and triglycerides (pairwise) (rs1427445). MyGeneLog™. https://www.mygenelog.com/variants/rs1427445

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