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Who was studied up to 14,112 European ancestry, Asian ancestry, African ancestry, Hispanic or Latin American cases, up to 1,032,106 European ancestry, Asian ancestry, African ancestry, Hispanic or Latin American controls.
The effect
Each copy of the A allele shifted the measure 0.475 higher (95% confidence interval 0.37-0.58); p = 2 × 10−18.
How common The A allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 5, band 5q32 — between genes, 4 kb from SPINK1.
What each result means
A/ATwo copies of the version the research linked to Acute pancreatitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Acute pancreatitis. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Acute pancreatitis. This is the starting point the study compared everyone against.
Scientific reports · 2024 · PMID 38491158 · open access
Questions about rs142703147
What is rs142703147?
rs142703147 is a single position in the genome, in or near the near SPINK1 gene. Published research associates it with acute pancreatitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs142703147 linked to?
On MyGeneLog this position is linked to Acute Pancreatitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs142703147 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs142703147 come from?
GWAS Catalog, Scientific reports 2024, PMID:38491158. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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