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Multiple myeloma (PheCode 204.4)

ANXA13 · rs142614314

Where this position leads

Condition: Multiple Myeloma

rs142614314 Condition: Multiple Myeloma Multiple Myeloma Condition rs142614314 rs142614314 ANXA13

What the study found

Who was studied 784 African American or Afro-Caribbean cases, 120,979 African American or Afro-Caribbean controls, 1,638 European ancestry cases, 449,163 European ancestry controls.

The effect Each copy of the C allele shifted the measure 2.99 lower (95% confidence interval 2.96-3.02); p = 9 × 10−12.

How common The C allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 8, band 8q24.13 — in an intron of ANXA13.

What each result means

C/C Two copies of the version the research linked to Multiple myeloma (PheCode 204.4). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Multiple myeloma (PheCode 204.4). That is a smaller link than two copies.
T/T No copy of the version the research linked to Multiple myeloma (PheCode 204.4). This is the starting point the study compared everyone against.
Source

Questions about rs142614314

What is rs142614314?

rs142614314 is a single position in the genome, in or near the ANXA13 gene. Published research associates it with multiple myeloma (phecode 204.4). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs142614314 linked to?

On MyGeneLog this position is linked to Multiple Myeloma. The research behind each link, and its sources, are set out on that condition page.

Does having rs142614314 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs142614314 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Multiple myeloma (PheCode 204.4) (rs142614314). MyGeneLog™. https://www.mygenelog.com/variants/rs142614314

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