near LINC03089 · rs142539486
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 7,708 European ancestry left or co-dominant individuals, 37,613 European ancestry right dominant individuals, 2,040 Sub-Saharan African ancestry left or co-dominant individuals, 8,280 Sub-Saharan African ancestry right dominant individuals, 738 Hispanic or Latin American left or co-dominant individuals, 3,717 Hispanic or Latin American right dominant individuals, 47 East Asian ancestry left or co-dominant individuals, 287 East Asian ancestry right dominant individuals, 7 South Asian ancestry left or co-dominant individuals, 25 South Asian ancestry right dominant individuals, 98 left or co-dominant individuals, 483 right dominant individuals.
The effect Each copy of the T allele carried 1.25 times the odds of Coronary dominance (left or co-dominant vs right dominant) (95% confidence interval 1.2-1.31); p = 3 × 10−22.
How common The T allele had a frequency of about 11% in the people studied.
Where it sits Chromosome 10, band 10q11.21 — between genes, 111.9 kb from LINC03089.
rs142539486 is a single position in the genome, in or near the near LINC03089 gene. Published research associates it with coronary dominance (left or co-dominant vs right dominant). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Cell 2025, PMID:40049164. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Coronary dominance (left or co-dominant vs right dominant) (rs142539486). MyGeneLog™. https://www.mygenelog.com/variants/rs142539486