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Energy expenditure

LOC107984317 · rs142343672

What the study found

Who was studied 5,461 European ancestry lean females, 2,726 European ancestry lean males, 6,563 European ancestry overweight or obese females, 4,020 European ancestry overweight or obese males..

The effect Each copy of the A allele shifted the measure 67 kcals higher (95% confidence interval 45-90); p = 5 × 10−9.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 11, band 11p15.1 — in an intron of SERGEF.

What each result means

A/A Two copies of the version the research linked to Energy expenditure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Energy expenditure. That is a smaller link than two copies.
G/G No copy of the version the research linked to Energy expenditure. This is the starting point the study compared everyone against.
Source

Questions about rs142343672

What is rs142343672?

rs142343672 is a single position in the genome, in or near the LOC107984317 gene. Published research associates it with energy expenditure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs142343672 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs142343672 come from?

GWAS Catalog, PLoS One 2018, PMID:30071075. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Energy expenditure (rs142343672). MyGeneLog™. https://www.mygenelog.com/variants/rs142343672

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