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Excessive daytime sleepiness

TMEM132B · rs142261172

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Excessive daytime sleepiness compared to the general population. (GWAS Catalog, Nat Genet 2016, PMID:27992416)

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Excessive daytime sleepiness. (GWAS Catalog, Nat Genet 2016, PMID:27992416)

G/G Published research associates this genotype with typical/baseline likelihood of Excessive daytime sleepiness — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2016, PMID:27992416)

Source: GWAS Catalog, Nat Genet 2016, PMID:27992416

Questions about rs142261172

What is rs142261172?

rs142261172 is a single position in the genome, in or near the TMEM132B gene. Published research associates it with excessive daytime sleepiness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs142261172 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs142261172 come from?

GWAS Catalog, Nat Genet 2016, PMID:27992416. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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