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Monounsaturated fatty acid levels

LPL · rs142084074

What the study found

Who was studied 128,922 European ancestry females.

The effect The reported allele is A; the catalogue records no effect size ; p = 3 × 10−14.

Where it sits Chromosome 8, band 8p21.3 — inside LPL.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Monounsaturated fatty acid levels compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Monounsaturated fatty acid levels.
G/G Published research associates this genotype with typical/baseline likelihood of Monounsaturated fatty acid levels — no copies of the reported risk allele.
Source

Questions about rs142084074

What is rs142084074?

rs142084074 is a single position in the genome, in or near the LPL gene. Published research associates it with monounsaturated fatty acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs142084074 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs142084074 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Monounsaturated fatty acid levels (rs142084074). MyGeneLog™. https://www.mygenelog.com/variants/rs142084074

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