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Creatinine in pregnancy

PLEKHM2 · rs142065151

What the study found

Who was studied 97,424 Chinese ancestry individuals; replicated in 47,248 Chinese ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.124 higher (95% confidence interval 0.093-0.154); p = 2 × 10−15.

How common The A allele had a frequency of about 14% in the people studied.

What each result means

A/A Two copies of the version the research linked to Creatinine in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Creatinine in pregnancy. That is a smaller link than two copies.
G/G No copy of the version the research linked to Creatinine in pregnancy. This is the starting point the study compared everyone against.
Source

Questions about rs142065151

What is rs142065151?

rs142065151 is a single position in the genome, in or near the PLEKHM2 gene. Published research associates it with creatinine in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs142065151 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs142065151 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Creatinine in pregnancy (rs142065151). MyGeneLog™. https://www.mygenelog.com/variants/rs142065151

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