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Veillonella abundance in stool

LYPLAL1-DT · rs141975840

What the study found

Who was studied 5,959 Finnish ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.434 higher (95% confidence interval 0.29-0.58); p = 5 × 10−9.

How common The C allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 1, band 1q41 — in an intron of LYPLAL1-DT.

What each result means

C/C Two copies of the version the research linked to Veillonella abundance in stool. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Veillonella abundance in stool. That is a smaller link than two copies.
T/T No copy of the version the research linked to Veillonella abundance in stool. This is the starting point the study compared everyone against.
Source

Questions about rs141975840

What is rs141975840?

rs141975840 is a single position in the genome, in or near the LYPLAL1-DT gene. Published research associates it with veillonella abundance in stool. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs141975840 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs141975840 come from?

GWAS Catalog, Nature genetics 2022, PMID:35115689. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Veillonella abundance in stool (rs141975840). MyGeneLog™. https://www.mygenelog.com/variants/rs141975840

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