Sensitive

Hemorrhagic stroke

near FOXL3 · rs141857337

What the study found

Who was studied 862 European ancestry cases, 17,021 European ancestry controls, 127 African American or Afro-Caribbean cases, 6,855 African American or Afro-Caribbean controls, 43 Hispanic or Latin American cases, 2,256 Hispanic or Latin American controls, 36 Asian ancestry cases, 734 Asian ancestry controls, 8 Native American ancestry cases, 34 Native American ancestry controls, 4 cases, 216 controls.

The effect Each copy of the A allele carried 455.40 times the odds of Hemorrhagic stroke (95% confidence interval 50.992149254560125-4067.0053863877174); p = 4 × 10−8.

Where it sits Chromosome 7, band 7p22.3 — between genes, 68.4 kb from FOXL3.

What each result means

A/A Two copies of the version the research linked to Hemorrhagic stroke. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Hemorrhagic stroke. That is a smaller link than two copies.
G/G No copy of the version the research linked to Hemorrhagic stroke. This is the starting point the study compared everyone against.
Source

Questions about rs141857337

What is rs141857337?

rs141857337 is a single position in the genome, in or near the near FOXL3 gene. Published research associates it with hemorrhagic stroke. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs141857337 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs141857337 come from?

GWAS Catalog, Stroke 2022, PMID:34727735. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hemorrhagic stroke (rs141857337). MyGeneLog™. https://www.mygenelog.com/variants/rs141857337

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