3 1915238Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI5Microsoft · Copilot0Amazon2Apple3Others8Total19Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 648 African American or Afro-Caribbean cases, 119,584 African American or Afro-Caribbean controls, 3,891 European ancestry cases, 439,202 European ancestry controls, 409 Hispanic or Latin American cases, 58,515 Hispanic or Latin American controls.
The effect
Each copy of the G allele shifted the measure 2.5 lower (95% confidence interval 2.46-2.54); p = 6 × 10−13.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 8, band 8q21.2 — between genes, 101.1 kb from TPM3P3.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Chronic fatigue syndrome (PheCode 798.1) — no copies of the reported risk allele.
C/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Chronic fatigue syndrome (PheCode 798.1).
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Chronic fatigue syndrome (PheCode 798.1) compared to the general population.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs141691232
What is rs141691232?
rs141691232 is a single position in the genome, in or near the near RALYL gene. Published research associates it with chronic fatigue syndrome (phecode 798.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs141691232 linked to?
On MyGeneLog this position is linked to Chronic Fatigue Syndrome (ME/CFS). The research behind each link, and its sources, are set out on that condition page.
Does having rs141691232 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs141691232 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 1915238Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI5Microsoft · Copilot0Amazon2Apple3Others8Total19Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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