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Atrial fibrillation/atrial flutter

near RNU6-1148P · rs141654122

Where this position leads

Condition: Atrial Fibrillation

rs141654122 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs141654122 rs141654122 near RNU6-11…

What the study found

Who was studied 29,212 European ancestry cases, 400,539 European ancestry controls, 4,150 East Asian ancestry cases, 155,540 East Asian ancestry controls.

The effect Each copy of the T allele shifted the measure 0.105 higher (95% confidence interval 0.083-0.126); p = 2 × 10−21.

Where it sits Chromosome 5, band 5q31.2 — between genes, 0.7 kb from RNU6-1148P.

What each result means

C/C No copy of the version the research linked to Atrial fibrillation/atrial flutter. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Atrial fibrillation/atrial flutter. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Atrial fibrillation/atrial flutter. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs141654122

What is rs141654122?

rs141654122 is a single position in the genome, in or near the near RNU6-1148P gene. Published research associates it with atrial fibrillation/atrial flutter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs141654122 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs141654122 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs141654122 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation/atrial flutter (rs141654122). MyGeneLog™. https://www.mygenelog.com/variants/rs141654122

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