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Telomere length (principal component 2)

near MIR663AHG · rs141469996

What the study found

Who was studied 438,351 Non-Finnish European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0831 higher (95% confidence interval 0.065-0.101); p = 5 × 10−19.

How common The C allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 20, band 20p11.1 — between genes, 23.9 kb from MIR663AHG.

What each result means

C/C Two copies of the version the research linked to Telomere length (principal component 2). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Telomere length (principal component 2). That is a smaller link than two copies.
T/T No copy of the version the research linked to Telomere length (principal component 2). This is the starting point the study compared everyone against.
Source

Questions about rs141469996

What is rs141469996?

rs141469996 is a single position in the genome, in or near the near MIR663AHG gene. Published research associates it with telomere length (principal component 2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs141469996 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs141469996 come from?

GWAS Catalog, Nature genetics 2024, PMID:39192095. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Telomere length (principal component 2) (rs141469996). MyGeneLog™. https://www.mygenelog.com/variants/rs141469996

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