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Leukocyte telomere length

SH3PXD2A · rs141240026

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 327,790 British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.069 higher (95% confidence interval 0.047-0.091); p = 2 × 10⁻¹⁰.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 10, band 10q24.33 — in an intron of SH3PXD2A.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Leukocyte telomere length compared to the general population.

A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Leukocyte telomere length.

C/C Published research associates this genotype with typical/baseline likelihood of Leukocyte telomere length — no copies of the reported risk allele.

Source

Whole exome sequencing analyses reveal novel genes in telomere length and their biomedical implications

Liu WS, Wu BS, Yang L, Chen SD, Zhang YR, Deng YT, Wu XR, He XY, Yang J, Feng JF, Cheng W, Xu YM

and 1 more — show all

Yu JT

GeroScience · 2024 · PMID 38837026

Questions about rs141240026

What is rs141240026?

rs141240026 is a single position in the genome, in or near the SH3PXD2A gene. Published research associates it with leukocyte telomere length. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs141240026 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs141240026 come from?

GWAS Catalog, GeroScience 2024, PMID:38837026. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Leukocyte telomere length (rs141240026). MyGeneLog™. https://www.mygenelog.com/variants/rs141240026

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