Standard

Systolic blood pressure

ACTRT1 · rs141216986

Where this position leads

Condition: Blood Pressure

rs141216986 Condition: Blood Pressure Blood Pressure Condition rs141216986 rs141216986 ACTRT1

What the study found

Who was studied 80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.818 higher; p = 2 × 10−8.

Where it sits Chromosome X, band Xq25 — between genes, 119.9 kb from KRT18P44.

What each result means

C/C Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
T/T No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs141216986

What is rs141216986?

rs141216986 is a single position in the genome, in or near the ACTRT1 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs141216986 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs141216986 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs141216986 come from?

GWAS Catalog, Nature genetics 2017, PMID:27841878. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs141216986). MyGeneLog™. https://www.mygenelog.com/variants/rs141216986

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