0 1512327Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 157 African American cases, 3,590 African American controls.
The effect
Each copy of the C allele carried 8.24 times the odds of Small cell lung cancer (95% confidence interval 4.24-16.02); p = 5 × 10−10.
Where it sits Chromosome 8, band 8q22.2 — in an intron of VPS13B.
What each result means
C/CTwo copies of the version the research linked to Small cell lung cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Small cell lung cancer. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Small cell lung cancer. This is the starting point the study compared everyone against.
American journal of human genetics · 2025 · PMID 40829600
Questions about rs141174940
What is rs141174940?
rs141174940 is a single position in the genome, in or near the VPS13B gene. Published research associates it with small cell lung cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs141174940 linked to?
On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs141174940 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs141174940 come from?
GWAS Catalog, American journal of human genetics 2025, PMID:40829600. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1512327Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Small cell lung cancer (rs141174940). MyGeneLog™. https://www.mygenelog.com/variants/rs141174940