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PRTG protein levels

PRTG · rs140985611

Where this position leads

Condition: Celiac Disease

rs140985611 Condition: Celiac Disease Celiac Disease Condition rs140985611 rs140985611 PRTG

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.391 lower (95% confidence interval 0.27-0.51); p = 1 × 10−11.

How common The G allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 15, band 15q21.3 — in an intron of PRTG.

What each result means

G/G Two copies of the version the research linked to PRTG protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to PRTG protein levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to PRTG protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs140985611

What is rs140985611?

rs140985611 is a single position in the genome, in or near the PRTG gene. Published research associates it with prtg protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs140985611 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs140985611 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs140985611 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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PRTG protein levels (rs140985611). MyGeneLog™. https://www.mygenelog.com/variants/rs140985611

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