Sensitive

Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1)

PITPNA · rs140948272

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) compared to the general population. (GWAS Catalog, Pharmacogenomics J 2016, PMID:26503814)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1). (GWAS Catalog, Pharmacogenomics J 2016, PMID:26503814)
T/T Published research associates this genotype with typical/baseline likelihood of Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) — no copies of the reported risk allele. (GWAS Catalog, Pharmacogenomics J 2016, PMID:26503814)

Source: GWAS Catalog, Pharmacogenomics J 2016, PMID:26503814

Questions about rs140948272

What is rs140948272?

rs140948272 is a single position in the genome, in or near the PITPNA gene. Published research associates it with response to bronchodilator in chronic obstructive pulmonary disease (change in fev1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs140948272 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs140948272 come from?

GWAS Catalog, Pharmacogenomics J 2016, PMID:26503814. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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