Sensitive

Alzheimer's disease or family history of Alzheimer's disease

near LINC01544 · rs140886023

Where this position leads

Condition: Alzheimer's Disease

rs140886023 Condition: Alzheimer's Disease Alzheimer's Disease Condition rs140886023 rs140886023 near LINC015…

What the study found

Who was studied 37,075 European, African, Admixed American, Asian, Middle Eastern, Oceanic or unknown ancestry cases, 367,392 European, African, Admixed American, Asian, Middle Eastern, Oceanic or unknown ancestry controls.

The effect The reported allele is T; the catalogue records no effect size ; p = 1 × 10−10.

Where it sits Chromosome 18, band 18q21.33 — between genes, 48.1 kb from LINC01544.

What each result means

C/C No copy of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs140886023

What is rs140886023?

rs140886023 is a single position in the genome, in or near the near LINC01544 gene. Published research associates it with alzheimer's disease or family history of alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs140886023 linked to?

On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs140886023 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs140886023 come from?

GWAS Catalog, Alzheimer's & dementia : the journal of the Alzheimer's Association 2025, PMID:39998322. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alzheimer's disease or family history of Alzheimer's disease (rs140886023). MyGeneLog™. https://www.mygenelog.com/variants/rs140886023

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