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Blue vs. green eyes

TYRP1 · rs1408799

What the study found

Who was studied 5,130 Icelandic individuals; replicated in 3,330 European ancestry individuals.

The effect Each copy of the C allele carried 1.40 times the odds of Blue vs. green eyes (95% confidence interval 1.25-1.57); p = 6 × 10−17.

How common The C allele had a frequency of about 75% in the people studied.

Where it sits Chromosome 9, band 9p23 — in an intron of LURAP1L-AS1.

What each result means

C/C Two copies of the version the research linked to Blue vs. green eyes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Blue vs. green eyes. That is a smaller link than two copies.
T/T No copy of the version the research linked to Blue vs. green eyes. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs1408799

What is rs1408799?

rs1408799 is a single position in the genome, in or near the TYRP1 gene. Published research associates it with blue vs. green eyes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs1408799?

Subjects that appear in the title or abstract of the same papers as this rsID include skin, sun and hair (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs1408799 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1408799 come from?

GWAS Catalog, Nat Genet 2008, PMID:18488028. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Blue vs. green eyes (rs1408799). MyGeneLog™. https://www.mygenelog.com/variants/rs1408799

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