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Apolipoprotein A1 levels

RFX6 · rs1406982

What the study found

Who was studied 393,193 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0143 higher (95% confidence interval 0.01-0.018); p = 1 × 10−11.

How common The T allele had a frequency of about 69% in the people studied.

Where it sits Chromosome 6, band 6q22.1 — in an intron of RFX6.

What each result means

A/A No copy of the version the research linked to Apolipoprotein A1 levels. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Apolipoprotein A1 levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Apolipoprotein A1 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1406982

What is rs1406982?

rs1406982 is a single position in the genome, in or near the RFX6 gene. Published research associates it with apolipoprotein a1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1406982 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1406982 come from?

GWAS Catalog, PLoS medicine 2020, PMID:32203549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Apolipoprotein A1 levels (rs1406982). MyGeneLog™. https://www.mygenelog.com/variants/rs1406982

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