OPHN1 · rs140488081
Where this position leads
What the study found
Who was studied 52,874 British ancestry males.
The effect Each copy of the T allele shifted the measure 0.397 lower; p = 5 × 10−61.
Where it sits Chromosome X, band Xq12 — in an intron of OPHN1.
rs140488081 is a single position in the genome, in or near the OPHN1 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PLoS Genet 2017, PMID:28196072. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Male-pattern baldness (rs140488081). MyGeneLog™. https://www.mygenelog.com/variants/rs140488081