Standard

Sex hormone-binding globulin levels

MINDY1 · rs140386498

What the study found

Who was studied 180,726 European ancestry men.

The effect Each copy of the T allele shifted the measure 0.0319 higher (95% confidence interval 0.021-0.043); p = 1 × 10−9.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 1, band 1q21.3 — a missense change in MINDY1.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Sex hormone-binding globulin levels — no copies of the reported risk allele.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Sex hormone-binding globulin levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Sex hormone-binding globulin levels compared to the general population.
Source

Questions about rs140386498

What is rs140386498?

rs140386498 is a single position in the genome, in or near the MINDY1 gene. Published research associates it with sex hormone-binding globulin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs140386498 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs140386498 come from?

GWAS Catalog, Nature medicine 2020, PMID:32042192. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sex hormone-binding globulin levels (rs140386498). MyGeneLog™. https://www.mygenelog.com/variants/rs140386498

← See all variants