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Uterine fibroids

LINC02627 · rs140287102

Where this position leads

Condition: Uterine Fibroids

rs140287102 Condition: Uterine Fibroids Uterine Fibroids Condition rs140287102 rs140287102 LINC02627

What the study found

Who was studied 53,711 European ancestry female cases, 380,441 European ancestry female controls, 14,905 East Asian ancestry female cases, 69,609 East Asian ancestry female controls, 14,905 Central Asian ancestry female cases, 69,609 Central Asian ancestry female controls, 14,905 South Asian ancestry female cases, 69,609 South Asian ancestry female controls, 5,678 African ancestry female cases, 15,760 African ancestry female controls.

The effect Each copy of the T allele shifted the measure 0.213 higher (95% confidence interval 0.15-0.28); p = 3 × 10−10.

Where it sits Chromosome 10, band 10q25.1 — inside LINC02627.

What each result means

C/C No copy of the version the research linked to Uterine fibroids. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Uterine fibroids. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Uterine fibroids. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs140287102

What is rs140287102?

rs140287102 is a single position in the genome, in or near the LINC02627 gene. Published research associates it with uterine fibroids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs140287102 linked to?

On MyGeneLog this position is linked to Uterine Fibroids. The research behind each link, and its sources, are set out on that condition page.

Does having rs140287102 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs140287102 come from?

GWAS Catalog, Nature communications 2025, PMID:40050615. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Uterine fibroids (rs140287102). MyGeneLog™. https://www.mygenelog.com/variants/rs140287102

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