Standard
Anterior chamber depth
HTR3D · rs1401999
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Anterior chamber depth compared to the general population.
C/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Anterior chamber depth.
G/G
Published research associates this genotype with typical/baseline likelihood of Anterior chamber depth — no copies of the reported risk allele.
Source
ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma
Nongpiur ME,
Khor CC,
Jia H,
Cornes BK,
Chen LJ,
Qiao C,
Nair KS,
Cheng CY,
Xu L,
George R,
Tan D,
Abu-Amero K
and 61 more — show all
Perera SA,
Ozaki M,
Mizoguchi T,
Kurimoto Y,
Low S,
Tajudin LS,
Ho CL,
Tham CC,
Soto I,
Chew PT,
Wong HT,
Shantha B,
Kuroda M,
Osman EA,
Tang G,
Fan S,
Meng H,
Wang H,
Feng B,
Yong VH,
Ting SM,
Li Y,
Wang YX,
Li Z,
Lavanya R,
Wu RY,
Zheng YF,
Su DH,
Loon SC,
Yong VK,
Allingham RR,
Hauser MA,
Soumittra N,
Ramprasad VL,
Waseem N,
Yaakub A,
Chia KS,
Kumaramanickavel G,
Wong TT,
How AC,
Chau TN,
Simmons CP,
Bei JX,
Zeng YX,
Bhattacharya SS,
Zhang M,
Tan DT,
Teo YY,
Al-Obeidan SA,
Hon DN,
Tai ES,
Saw SM,
Foster PJ,
Vijaya L,
Jonas JB,
Wong TY,
John SW,
Pang CP,
Vithana EN,
Wang N,
Aung T
PLoS genetics · 2014 · PMID 24603532 · open access
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs1401999
What is rs1401999?
rs1401999 is a single position in the genome, in or near the HTR3D gene. Published research associates it with anterior chamber depth. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs1401999?
Subjects that appear in the title or abstract of the same papers as this rsID include short-sightedness and screens (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs1401999 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1401999 come from?
GWAS Catalog, PLoS Genet 2014, PMID:24603532. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants