A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Breast cancer compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Breast cancer.
G/GPublished research associates this genotype with typical/baseline likelihood of Breast cancer — no copies of the reported risk allele.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs140068132
What is rs140068132?
rs140068132 is a single position in the genome, in or near the ESR1 gene. Published research associates it with breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs140068132 linked to?
On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs140068132?
Subjects that appear in the title or abstract of the same papers as this rsID include menopause (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs140068132 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs140068132 come from?
GWAS Catalog, Nat Commun 2014, PMID:25327703. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.