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Blood protein levels in cardiovascular risk

near SLC43A3 · rs140000161

What the study found

Who was studied 3,394 European ancestry individuals; replicated in 2,639 individuals.

The effect Each copy of the A allele shifted the measure 0.37 lower; p = 1 × 10−16.

How common The A allele had a frequency of about 91% in the people studied.

Where it sits Chromosome 11, band 11q12.1 — between genes, 3.4 kb from SLC43A3.

What each result means

A/A Two copies of the version the research linked to Blood protein levels in cardiovascular risk. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Blood protein levels in cardiovascular risk. That is a smaller link than two copies.
G/G No copy of the version the research linked to Blood protein levels in cardiovascular risk. This is the starting point the study compared everyone against.
Source

Questions about rs140000161

What is rs140000161?

rs140000161 is a single position in the genome, in or near the near SLC43A3 gene. Published research associates it with blood protein levels in cardiovascular risk. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs140000161 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs140000161 come from?

GWAS Catalog, PLoS genetics 2017, PMID:28369058. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Blood protein levels in cardiovascular risk (rs140000161). MyGeneLog™. https://www.mygenelog.com/variants/rs140000161

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