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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 227 African American or Afro-Caribbean cases, 121,044 African American or Afro-Caribbean controls, 1,071 European ancestry cases, 447,249 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 1.84 lower (95% confidence interval 1.78-1.91); p = 4 × 10−11.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 14, band 14q23.1 — in an intron of DAAM1.
What each result means
A/APublished research associates this genotype with typical/baseline likelihood of Anticoagulants causing adverse effects (PheCode 964.1) — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Anticoagulants causing adverse effects (PheCode 964.1).
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Anticoagulants causing adverse effects (PheCode 964.1) compared to the general population.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs139950837
What is rs139950837?
rs139950837 is a single position in the genome, in or near the DAAM1 gene. Published research associates it with anticoagulants causing adverse effects (phecode 964.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs139950837 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs139950837 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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