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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 5,359 Icelandic ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.683 lower (95% confidence interval 0.52-0.85); p = 4 × 10−16.
How common The A allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 11, band 11p15.1 — in an intron of LDHC.
What each result means
A/ATwo copies of the version the research linked to Serum levels of protein CRIM1. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Serum levels of protein CRIM1. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Serum levels of protein CRIM1. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 35078996 · open access
Questions about rs139946387
What is rs139946387?
rs139946387 is a single position in the genome, in or near the LDHC gene. Published research associates it with serum levels of protein crim1. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs139946387 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs139946387 come from?
GWAS Catalog, Nature communications 2022, PMID:35078996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Serum levels of protein CRIM1 (rs139946387). MyGeneLog™. https://www.mygenelog.com/variants/rs139946387