0 1614722Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot7Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 54 African ancestry cases, 28 Hispanic/Latino cases, 18 East Asian ancestry cases, 728 European ancestry cases, 43 South Asian ancestry cases, 593 African ancestry controls, 92 Hispanic/Latino controls, 121 East Asian ancestry controls, 18,791 European ancestry controls, 595 South Asian ancestry controls.
The effect
Each copy of the T allele shifted the measure 1.25 lower (95% confidence interval 0.91-1.59); p = 5 × 10−13.
How common The T allele had a frequency of about 99% in the people studied.
Where it sits Chromosome 11, band 11q12.1 — between genes, 6.2 kb from FADS2B.
What each result means
C/CNo copy of the version the research linked to Hypertrophic cardiomyopathy (sarcomere positive). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Hypertrophic cardiomyopathy (sarcomere positive). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Hypertrophic cardiomyopathy (sarcomere positive). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs139913353 is a single position in the genome, in or near the OR5AK2 gene. Published research associates it with hypertrophic cardiomyopathy (sarcomere positive). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs139913353 linked to?
On MyGeneLog this position is linked to Hypertrophic Cardiomyopathy. The research behind each link, and its sources, are set out on that condition page.
Does having rs139913353 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs139913353 come from?
GWAS Catalog, Nature genetics 2021, PMID:33495597. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1614722Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot7Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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