Sensitive

Chronotype and breast cancer

TNRC6B · rs139909

Where this position leads

Condition: Breast Cancer

rs139909 Condition: Breast Cancer Breast Cancer Condition rs139909 rs139909 TNRC6B

What the study found

Who was studied 133,384 European ancestry breast cancer cases, 113,789 European ancestry controls, 449,734 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 3 × 10−18.

Where it sits Chromosome 22, band 22q13.1 — in an intron of TNRC6B.

What each result means

C/C Two copies of the version the research linked to Chronotype and breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Chronotype and breast cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Chronotype and breast cancer. This is the starting point the study compared everyone against.
Source

Questions about rs139909

What is rs139909?

rs139909 is a single position in the genome, in or near the TNRC6B gene. Published research associates it with chronotype and breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs139909 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs139909 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs139909 come from?

GWAS Catalog, Journal of sleep research 2024, PMID:37380357. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Chronotype and breast cancer (rs139909). MyGeneLog™. https://www.mygenelog.com/variants/rs139909

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