Sensitive

Prostate cancer

PIK3C2B · rs1398148

Where this position leads

Condition: Prostate Cancer

rs1398148 Condition: Prostate Cancer Prostate Cancer Condition rs1398148 rs1398148 PIK3C2B

What the study found

Who was studied 10,792 European ancestry male cases, 190,694 European ancestry male controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 5 × 10−8.

Where it sits Chromosome 1, band 1q32.1 — in an intron of PIK3C2B.

What each result means

C/C Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
G/G No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
Source

Questions about rs1398148

What is rs1398148?

rs1398148 is a single position in the genome, in or near the PIK3C2B gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1398148 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs1398148 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1398148 come from?

GWAS Catalog, Nature communications 2020, PMID:32887889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer (rs1398148). MyGeneLog™. https://www.mygenelog.com/variants/rs1398148

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