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Lipoprotein (a) levels

LPA · rs139699952

What the study found

Who was studied 13,781 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 6.79 mg/dL higher (95% confidence interval 4.46-9.12); p = 5 × 10−11.

Where it sits Chromosome 6, band 6q26 — between genes, 46.3 kb from PLG.

What each result means

C/C Two copies of the version the research linked to Lipoprotein (a) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Lipoprotein (a) levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Lipoprotein (a) levels. This is the starting point the study compared everyone against.
Source

Questions about rs139699952

What is rs139699952?

rs139699952 is a single position in the genome, in or near the LPA gene. Published research associates it with lipoprotein (a) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs139699952 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs139699952 come from?

GWAS Catalog, Journal of lipid research 2017, PMID:28512139. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lipoprotein (a) levels (rs139699952). MyGeneLog™. https://www.mygenelog.com/variants/rs139699952

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