A/APublished research associates this genotype with typical/baseline likelihood of Major depression and alcohol dependence — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Major depression and alcohol dependence.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Major depression and alcohol dependence compared to the general population.
rs139438618 is a single position in the genome, in or near the SEMA3A gene. Published research associates it with major depression and alcohol dependence. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs139438618 linked to?
On MyGeneLog this position is linked to Major Depression and Alcohol Dependence (Comorbid). The research behind each link, and its sources, are set out on that condition page.
Does having rs139438618 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs139438618 come from?
GWAS Catalog, JAMA Psychiatry 2017, PMID:29071344. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.