USP2-AS1 · rs139137459
Where this position leads
Condition: Human Lifespan and Longevity
What the study found
Who was studied 7,182 cases, 79,767 controls.
The effect Each copy of the G allele shifted the measure 0.0906 lower (95% confidence interval 0.059-0.122); p = 3 × 10−8.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 11, band 11q23.3 — in an intron of USP2-AS1.
rs139137459 is a single position in the genome, in or near the USP2-AS1 gene. Published research associates it with parental longevity (both parents in top 10%). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Human Lifespan and Longevity. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Aging (Albany NY) 2017, PMID:29227965. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Parental longevity (both parents in top 10%) (rs139137459). MyGeneLog™. https://www.mygenelog.com/variants/rs139137459