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Ascending thoracic aortic diameter

TEX41 · rs138963986

What the study found

Who was studied 33,637 European ancestry individuals, 5,057 individuals.

The effect Each copy of the G allele shifted the measure 0.068 higher; p = 4 × 10−8.

How common The G allele had a frequency of about 93% in the people studied.

Where it sits Chromosome 2, band 2q22.3 — in an intron of TEX41.

What each result means

A/A No copy of the version the research linked to Ascending thoracic aortic diameter. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Ascending thoracic aortic diameter. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Ascending thoracic aortic diameter. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs138963986

What is rs138963986?

rs138963986 is a single position in the genome, in or near the TEX41 gene. Published research associates it with ascending thoracic aortic diameter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs138963986 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs138963986 come from?

GWAS Catalog, Nature genetics 2022, PMID:34837083. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Ascending thoracic aortic diameter (rs138963986). MyGeneLog™. https://www.mygenelog.com/variants/rs138963986

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