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Secreted frizzled-related protein 1 levels (SFRP1.3221.54.1)

near SFRP1 · rs138942288

What the study found

Who was studied 3,301 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 1.4 higher (95% confidence interval 1.05-1.75); p = 4 × 10−15.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 8, band 8p11.21 — between genes, 26.6 kb from SFRP1.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Secreted frizzled-related protein 1 levels (SFRP1.3221.54.1) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Secreted frizzled-related protein 1 levels (SFRP1.3221.54.1).
G/G Published research associates this genotype with typical/baseline likelihood of Secreted frizzled-related protein 1 levels (SFRP1.3221.54.1) — no copies of the reported risk allele.
Source

Questions about rs138942288

What is rs138942288?

rs138942288 is a single position in the genome, in or near the near SFRP1 gene. Published research associates it with secreted frizzled-related protein 1 levels (sfrp1.3221.54.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs138942288 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs138942288 come from?

GWAS Catalog, Nature 2018, PMID:29875488. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Secreted frizzled-related protein 1 levels (SFRP1.3221.54.1) (rs138942288). MyGeneLog™. https://www.mygenelog.com/variants/rs138942288

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