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Sex hormone-binding globulin levels adjusted for BMI

NFIC · rs138699938

What the study found

Who was studied 368,929 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0669 higher (95% confidence interval 0.047-0.087); p = 2 × 10−11.

How common The C allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 19, band 19p13.3 — a missense change in NFIC.

What each result means

C/C Two copies of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. That is a smaller link than two copies.
T/T No copy of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. This is the starting point the study compared everyone against.
Source

Questions about rs138699938

What is rs138699938?

rs138699938 is a single position in the genome, in or near the NFIC gene. Published research associates it with sex hormone-binding globulin levels adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs138699938 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs138699938 come from?

GWAS Catalog, Nature medicine 2020, PMID:32042192. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sex hormone-binding globulin levels adjusted for BMI (rs138699938). MyGeneLog™. https://www.mygenelog.com/variants/rs138699938

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