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Who was studied 4,383 Mexican ancestry individuals; replicated in 7,876 Latin American/Hispanic individuals, European ancestry individuals (Global Lipids Genetics Consortium et al, 2013).
The effect
Each copy of the T allele shifted the measure 0.148 higher (95% confidence interval 0.097-0.199); p = 8 × 10−9.
How common The T allele had a frequency of about 92% in the people studied.
Where it sits Chromosome 19, band 19p13.2 — in an intron of KANK2.
What each result means
C/CNo copy of the version the research linked to Cholesterol, total. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Cholesterol, total. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Cholesterol, total. That is the strongest link of the three results. A link in a study is not a diagnosis.
Scientific reports · 2016 · PMID 26780889 · open access
Questions about rs138534124
What is rs138534124?
rs138534124 is a single position in the genome, in or near the KANK2 gene. Published research associates it with cholesterol, total. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs138534124 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs138534124 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs138534124 come from?
GWAS Catalog, Sci Rep 2016, PMID:26780889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cholesterol, total (rs138534124). MyGeneLog™. https://www.mygenelog.com/variants/rs138534124