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Triglyceride levels in chylomicrons and extremely large VLDL

AGPAT4 · rs138458033

What the study found

Who was studied 115,082 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.246 higher (95% confidence interval 0.21-0.28); p = 2 × 10−41.

How common The C allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 6, band 6q26 — in an intron of AGPAT4.

What each result means

C/C Two copies of the version the research linked to Triglyceride levels in chylomicrons and extremely large VLDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Triglyceride levels in chylomicrons and extremely large VLDL. That is a smaller link than two copies.
T/T No copy of the version the research linked to Triglyceride levels in chylomicrons and extremely large VLDL. This is the starting point the study compared everyone against.
Source

Questions about rs138458033

What is rs138458033?

rs138458033 is a single position in the genome, in or near the AGPAT4 gene. Published research associates it with triglyceride levels in chylomicrons and extremely large vldl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs138458033 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs138458033 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Triglyceride levels in chylomicrons and extremely large VLDL (rs138458033). MyGeneLog™. https://www.mygenelog.com/variants/rs138458033

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